5Y2Z

Crystal structure of human LGI1 EPTP-ADAM22 complex

5Y2Z の概要

• エントリーDOI: 10.2210/pdb5y2z/pdb
• 分子名称: Disintegrin and metalloproteinase domain-containing protein 22, Leucine-rich glioma-inactivated protein 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• 機能のキーワード: epilepsy, synapse, adam, eptp, wd40, cell adhesion
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 583485.08

構造登録者

Yamagata, A.,Fukai, S. (登録日: 2017-07-27, 公開日: 2018-05-02, 最終更新日: 2023-11-22)

• 主引用文献: Yamagata, A.,Miyazaki, Y.,Yokoi, N.,Shigematsu, H.,Sato, Y.,Goto-Ito, S.,Maeda, A.,Goto, T.,Sanbo, M.,Hirabayashi, M.,Shirouzu, M.,Fukata, Y.,Fukata, M.,Fukai, S.; Structural basis of epilepsy-related ligand-receptor complex LGI1-ADAM22.; Nat Commun, 9:1546-1546, 2018; PubMed: 29670100; DOI: 10.1038/s41467-018-03947-w

実験手法

X-RAY DIFFRACTION (2.67 Å)