5XET

Crystal structure of Mycobacterium tuberculosis methionyl-tRNA synthetase bound by methionyl-adenylate (Met-AMP)

Summary for 5XET

• Entry DOI: 10.2210/pdb5xet/pdb
• Descriptor: Methionine--tRNA ligase, [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl] (2S)-2-azanyl-4-methylsulfanyl-butanoate, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: synthetase, aminoacyl-trna synthetase, complex, atp, ligase
• Biological source: Mycobacterium tuberculosis H37Ra
• Total number of polymer chains: 1
• Total formula weight: 60081.83

Authors

Wang, W.,Qin, B.,Wojdyla, J.A.,Wang, M.,Gao, X.,Cui, S. (deposition date: 2017-04-06, release date: 2018-07-11, Last modification date: 2023-11-22)

• Primary citation: Wang, W.,Qin, B.,Wojdyla, J.A.,Wang, M.,Gao, X.,Cui, S.; Structural characterization of free-state and product-stateMycobacterium tuberculosismethionyl-tRNA synthetase reveals an induced-fit ligand-recognition mechanism.; IUCrJ, 5:478-490, 2018; PubMed: 30002848; DOI: 10.1107/S2052252518008217

Experimental method

X-RAY DIFFRACTION (2.38 Å)