5XET
Crystal structure of Mycobacterium tuberculosis methionyl-tRNA synthetase bound by methionyl-adenylate (Met-AMP)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | Methionine--tRNA ligase | polymer | 529 | 59419.8 | 1 | UniProt (A5U150) Pfam (PF09334) Pfam (PF19303) | Mycobacterium tuberculosis H37Ra | Methionyl-tRNA synthetase,MetRS |
| 2 | B (C) | [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl] (2S)-2-azanyl-4-methylsulfanyl-butanoate | non-polymer | 478.4 | 1 | Chemie (ME8) | |||
| 3 | C (C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | D, E, F, G, H (C) | MAGNESIUM ION | non-polymer | 24.3 | 5 | Chemie (MG) | |||
| 5 | I (C) | water | water | 18.0 | 180 | Chemie (HOH) |
Sequence modifications
C: 1 - 519 (UniProt: A5U150)
| PDB | External Database | Details |
|---|---|---|
| Met -7 | - | expression tag |
| Gly -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| Arg 520 | - | expression tag |
| Ser 521 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 59419.8 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 662.0 | |
| All* | Total formula weight | 60081.8 |
