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5XET

Crystal structure of Mycobacterium tuberculosis methionyl-tRNA synthetase bound by methionyl-adenylate (Met-AMP)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(C)
Methionine--tRNA ligasepolymer52959419.81UniProt (A5U150)
Pfam (PF09334)
Pfam (PF19303)
Mycobacterium tuberculosis H37RaMethionyl-tRNA synthetase,MetRS
2B
(C)
[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl] (2S)-2-azanyl-4-methylsulfanyl-butanoatenon-polymer478.41Chemie (ME8)
3C
(C)
1,2-ETHANEDIOLnon-polymer62.11Chemie (EDO)
4D, E, F, G, H
(C)
MAGNESIUM IONnon-polymer24.35Chemie (MG)
5I
(C)
waterwater18.0180Chemie (HOH)
Sequence modifications
C: 1 - 519 (UniProt: A5U150)
PDBExternal DatabaseDetails
Met -7-expression tag
Gly -6-expression tag
His -5-expression tag
His -4-expression tag
His -3-expression tag
His -2-expression tag
His -1-expression tag
His 0-expression tag
Arg 520-expression tag
Ser 521-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight59419.8
Non-Polymers*Number of molecules7
Total formula weight662.0
All*Total formula weight60081.8
*Water molecules are not included.

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PDB entries from 2024-11-06

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