5XDS
Crystal structure of Mycobacterium tuberculosis HisB bound with an inhibitor
Summary for 5XDS
| Entry DOI | 10.2210/pdb5xds/pdb |
| Descriptor | Imidazoleglycerol-phosphate dehydratase, MANGANESE (II) ION, CHLORIDE ION, ... (5 entities in total) |
| Functional Keywords | mycobacterium tuberculosis, tuberculosis, imidazoleglycerol phosphate dehydratase, drug target, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
| Biological source | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
| Cellular location | Cytoplasm : P9WML9 |
| Total number of polymer chains | 1 |
| Total formula weight | 23934.99 |
| Authors | Kumar, D.,Jha, B.,Ahangar, M.S.,Kumar, B.B. (deposition date: 2017-03-29, release date: 2018-04-04, Last modification date: 2023-11-22) |
| Primary citation | Kumar, D.,Jha, B.,Bhatia, I.,Ashraf, A.,Dwivedy, A.,Biswal, B.K. Characterization of a triazole scaffold compound as an inhibitor of Mycobacterium tuberculosis imidazoleglycerol-phosphate dehydratase. Proteins, 2021 Cited by PubMed: 34288118DOI: 10.1002/prot.26181 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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