5XDS
Crystal structure of Mycobacterium tuberculosis HisB bound with an inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Imidazoleglycerol-phosphate dehydratase | polymer | 216 | 23633.5 | 1 | UniProt (P9WML9) Pfam (PF00475) In PDB | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | IGPD |
| 2 | A | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 3 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | A | (2S)-2-azanyl-3-(4H-1,2,4-triazol-3-yl)propanoic acid | non-polymer | 156.1 | 1 | Chemie (83O) | |||
| 5 | water | water | 18.0 | 194 | Chemie (HOH) |
Sequence modifications
A: 2 - 210 (UniProt: P9WML9)
| PDB | External Database | Details |
|---|---|---|
| Met -5 | - | initiating methionine |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| His 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23633.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 301.5 | |
| All* | Total formula weight | 23935.0 |
