Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000105 | biological_process | L-histidine biosynthetic process |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004424 | molecular_function | imidazoleglycerol-phosphate dehydratase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue MN A 301 |
| Chain | Residue |
| A | HIS73 |
| A | GLU77 |
| A | HIS152 |
| A | HIS177 |
| A | 83O304 |
| A | HOH436 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MN A 302 |
| Chain | Residue |
| A | GLU180 |
| A | 83O304 |
| A | HOH426 |
| A | HIS47 |
| A | HIS74 |
| A | HIS176 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue CL A 303 |
| Chain | Residue |
| A | ARG168 |
| A | ARG168 |
| A | ARG168 |
| A | HOH555 |
| A | HOH555 |
| A | HOH555 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | binding site for residue 83O A 304 |
| Chain | Residue |
| A | HIS73 |
| A | HIS74 |
| A | GLU77 |
| A | MET107 |
| A | ARG121 |
| A | HIS176 |
| A | HIS177 |
| A | GLU180 |
| A | MN301 |
| A | MN302 |
| A | HOH408 |
| A | HOH426 |
| A | HOH434 |
Functional Information from PROSITE/UniProt
| site_id | PS00954 |
| Number of Residues | 14 |
| Details | IGP_DEHYDRATASE_1 Imidazoleglycerol-phosphate dehydratase signature 1. IEaHHtiEdtAIAL |
| Chain | Residue | Details |
| A | ILE70-LEU83 | |
| site_id | PS00955 |
| Number of Residues | 13 |
| Details | IGP_DEHYDRATASE_2 Imidazoleglycerol-phosphate dehydratase signature 2. GrDpHHitEAqYK |
| Chain | Residue | Details |
| A | GLY172-LYS184 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"O23346","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24311587","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5ZQN","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24311587","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4GQU","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24311587","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XDS","evidenceCode":"ECO:0007744"}]} |
