5X07
Crystal structure of FOXA2 DNA binding domain bound to a full consensus DNA site
Summary for 5X07
Entry DOI | 10.2210/pdb5x07/pdb |
Descriptor | DNA (5'-D(*TP*CP*TP*TP*GP*TP*TP*TP*AP*CP*AP*TP*TP*TP*TP*G)-3'), DNA (5'-D(*CP*AP*AP*AP*AP*TP*GP*TP*AP*AP*AP*CP*AP*AP*GP*A)-3'), Hepatocyte nuclear factor 3-beta (3 entities in total) |
Functional Keywords | foxa2, forkhead domain, consensus binding site, isothermal titration calorimetry, itc, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus : Q9Y261 |
Total number of polymer chains | 12 |
Total formula weight | 88738.59 |
Authors | |
Primary citation | Li, J.,Machado, A.C.D.,Guo, M.,Sagendorf, J.M.,Zhou, Z.,Jiang, L.,Chen, X.,Wu, D.,Qu, L.,Chen, Z.,Chen, L.,Rohs, R.,Chen, Y. Structure of the Forkhead Domain of FOXA2 Bound to a Complete DNA Consensus Site Biochemistry, 56:3745-3753, 2017 Cited by PubMed: 28644006DOI: 10.1021/acs.biochem.7b00211 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.796 Å) |
Structure validation
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