5WZU
Crystal structure of human secreted phospholipase A2 group IIE with Compound 24
Summary for 5WZU
Entry DOI | 10.2210/pdb5wzu/pdb |
Related | 5WZM 5WZO 5WZS 5WZT 5WZV 5WZW |
Descriptor | Group IIE secretory phospholipase A2, CALCIUM ION, 2-[2-methyl-3-oxamoyl-1-[[2-(trifluoromethyl)phenyl]methyl]indol-4-yl]oxyethanoic acid, ... (7 entities in total) |
Functional Keywords | phospholipase a2, hydrolase-inhibitor complex, hydrolase/inhibitor |
Biological source | Homo sapiens (Human) |
Cellular location | Secreted: Q9NZK7 |
Total number of polymer chains | 1 |
Total formula weight | 14701.71 |
Authors | |
Primary citation | Hou, S.,Xu, T.,Xu, J.,Qu, L.,Xu, Y.,Chen, L.,Liu, J. Structural basis for functional selectivity and ligand recognition revealed by crystal structures of human secreted phospholipase A2 group IIE Sci Rep, 7:10815-10815, 2017 Cited by PubMed: 28883454DOI: 10.1038/s41598-017-11219-8 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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