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5WZU

Crystal structure of human secreted phospholipase A2 group IIE with Compound 24

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Group IIE secretory phospholipase A2polymer12313986.11UniProt (Q9NZK7)
Pfam (PF00068)
Homo sapiens (Human)sPLA2-IIE,Phosphatidylcholine 2-acylhydrolase 2E
2B
(A)
CALCIUM IONnon-polymer40.11Chemie (CA)
3C
(A)
2-[2-methyl-3-oxamoyl-1-[[2-(trifluoromethyl)phenyl]methyl]indol-4-yl]oxyethanoic acidnon-polymer434.41Chemie (7W3)
4D
(A)
DIMETHYL SULFOXIDEnon-polymer78.11Chemie (DMS)
5E
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
6F, G
(A)
CHLORIDE IONnon-polymer35.52Chemie (CL)
7H
(A)
waterwater18.091Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight13986.1
Non-Polymers*Number of molecules6
Total formula weight715.6
All*Total formula weight14701.7
*Water molecules are not included.

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PDB entries from 2025-12-24

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