5WYN
HtrA2 Pathogenic Mutant
Summary for 5WYN
Entry DOI | 10.2210/pdb5wyn/pdb |
Descriptor | Serine protease HTRA2, mitochondrial, CHLORIDE ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (4 entities in total) |
Functional Keywords | neurodegeneration, pathogenic mutant, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 36424.94 |
Authors | Wagh, A.R.,Bose, K. (deposition date: 2017-01-13, release date: 2018-08-08, Last modification date: 2023-11-22) |
Primary citation | Wagh, A.R.,Bose, K. Structural basis of inactivation of human counterpart of mouse motor neuron degeneration 2 mutant in serine protease HtrA2 Biosci. Rep., 38:-, 2018 Cited by PubMed: 30068699DOI: 10.1042/BSR20181072 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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