5WXP
Crystal structure of uPA in complex with upain-2-3-W3A
Summary for 5WXP
Entry DOI | 10.2210/pdb5wxp/pdb |
Related | 5WXF 5WXO 5WXQ 5WXR 5WXS 5WXT |
Descriptor | Urokinase-type plasminogen activator chain B, upain-2-3-W3A peptide, ALANINE, ... (5 entities in total) |
Functional Keywords | serine proteases, upa, pepetide inhibitors, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 29136.17 |
Authors | |
Primary citation | Jiang, L.,Oldenburg, E.,Kromann-Hansen, T.,Xu, P.,Jensen, J.K.,Andreasen, P.A.,Huang, M. Cleavage of peptidic inhibitors by target protease is caused by peptide conformational transition. Biochim. Biophys. Acta, 1862:2017-2023, 2018 Cited by PubMed: 29959058DOI: 10.1016/j.bbagen.2018.06.016 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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