5WXP
Crystal structure of uPA in complex with upain-2-3-W3A
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | U | Urokinase-type plasminogen activator chain B | polymer | 253 | 28442.4 | 1 | UniProt (P00749) Pfam (PF00089) In PDB | Homo sapiens (Human) | uPA |
2 | P | upain-2-3-W3A peptide | polymer | 4 | 483.5 | 1 | Phage display vector pTDisp | ||
3 | P | ALANINE | non-polymer | 89.1 | 1 | Chemie (ALA) | |||
4 | P | CYSTEINE | non-polymer | 121.2 | 1 | Chemie (CYS) | |||
5 | water | water | 18.0 | 69 | Chemie (HOH) |
Sequence modifications
U: 16 - 250 (UniProt: P00749)
PDB | External Database | Details |
---|---|---|
Ala 122 | Cys 299 | engineered mutation |
Gln 145 | Asn 322 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 28925.9 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 210.3 | |
All* | Total formula weight | 29136.2 |