5WXP
Crystal structure of uPA in complex with upain-2-3-W3A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (U) | Urokinase-type plasminogen activator chain B | polymer | 253 | 28442.4 | 1 | UniProt (P00749) Pfam (PF00089) | Homo sapiens (Human) | uPA |
| 2 | B (P) | upain-2-3-W3A peptide | polymer | 4 | 483.5 | 1 | Phage display vector pTDisp | ||
| 3 | C (P) | ALANINE | non-polymer | 89.1 | 1 | Chemie (ALA) | |||
| 4 | D (P) | CYSTEINE | non-polymer | 121.2 | 1 | Chemie (CYS) | |||
| 5 | E (U) | water | water | 18.0 | 69 | Chemie (HOH) |
Sequence modifications
U: 16 - 250 (UniProt: P00749)
| PDB | External Database | Details |
|---|---|---|
| Ala 122 | Cys 299 | engineered mutation |
| Gln 145 | Asn 322 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28925.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 210.3 | |
| All* | Total formula weight | 29136.2 |
