5WE7
Crystal structure of the influenza virus PA endonuclease in complex with an inhibitor - SRI-29782
Summary for 5WE7
Entry DOI | 10.2210/pdb5we7/pdb |
Related | 5W3I 5W44 5W73 5W7U 5W92 5W9G 5WA6 5WA7 5WAP 5WB3 5WCS 5WCT 5WDC 5WDN 5WDW |
Descriptor | Polymerase acidic protein, MANGANESE (II) ION, 2-{(2R)-1-[2-(4-chlorophenoxy)-2-methylpropanoyl]pyrrolidin-2-yl}-5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxylic acid, ... (5 entities in total) |
Functional Keywords | virus, nuclease, transcription, cap-snatching, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Influenza A virus More |
Total number of polymer chains | 1 |
Total formula weight | 22635.95 |
Authors | Kumar, G.,White, S.W. (deposition date: 2017-07-07, release date: 2018-01-03, Last modification date: 2024-03-13) |
Primary citation | Kumar, G.,White, S.W. Crystal structure of the influenza virus PA endonuclease in complex with an inhibitor - SRI-29782 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.12 Å) |
Structure validation
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