5W6V
The Structure of human Argonaute-1 in complex with the hook motif of human GW182
Summary for 5W6V
Entry DOI | 10.2210/pdb5w6v/pdb |
Descriptor | Protein argonaute-1, RNA (5'-R(P*AP*AP*UP*AP*UP*UP*AP*AP*AP*A)-3'), Trinucleotide repeat-containing gene 6A protein, ... (4 entities in total) |
Functional Keywords | rna interference, rna binding proteins, gw motif, gene regulation-rna complex, gene regulation/rna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 103893.95 |
Authors | Elkayam, E.,Faehnle, C.R.,Joshua-Tor, L. (deposition date: 2017-06-17, release date: 2017-07-26, Last modification date: 2023-10-04) |
Primary citation | Elkayam, E.,Faehnle, C.R.,Morales, M.,Sun, J.,Li, H.,Joshua-Tor, L. Multivalent Recruitment of Human Argonaute by GW182. Mol. Cell, 67:646-658.e3, 2017 Cited by PubMed: 28781232DOI: 10.1016/j.molcel.2017.07.007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.828 Å) |
Structure validation
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