5VQF

Crystal Structure of pro-TGF-beta 1

5VQF の概要

• エントリーDOI: 10.2210/pdb5vqf/pdb
• 分子名称: Transforming growth factor beta-1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• 機能のキーワード: pro-complex, latency, homodimer, protein binding
• 由来する生物種: Sus scrofa (Pig)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 167164.98

構造登録者

Zhao, B.,Xu, S.,Dong, X.,Lu, C.,Springer, T.A. (登録日: 2017-05-08, 公開日: 2017-11-15, 最終更新日: 2023-10-04)

• 主引用文献: Zhao, B.,Xu, S.,Dong, X.,Lu, C.,Springer, T.A.; Prodomain-growth factor swapping in the structure of pro-TGF-beta 1.; J. Biol. Chem., 293:1579-1589, 2018; PubMed: 29109152; DOI: 10.1074/jbc.M117.809657

実験手法

X-RAY DIFFRACTION (2.9 Å)