5VK3

Apo ctPRC2 with E840A and K852D mutations in Ezh2

Summary for 5VK3

• Entry DOI: 10.2210/pdb5vk3/pdb
• Related: 5BJS 5TQR
• Descriptor: Polycomb Protein EED, Histone-lysine N-methyltransferase EZH2,Polycomb protein SUZ12, ZINC ION, ... (4 entities in total)
• Functional Keywords: transferase
• Biological source: Chaetomium thermophilum; More
• Total number of polymer chains: 2
• Total formula weight: 173342.11

Authors

Bratkowski, M.A.,Liu, X. (deposition date: 2017-04-20, release date: 2017-06-14, Last modification date: 2023-10-04)

• Primary citation: Bratkowski, M.,Yang, X.,Liu, X.; Polycomb repressive complex 2 in an autoinhibited state.; J. Biol. Chem., 292:13323-13332, 2017; PubMed: 28607149; DOI: 10.1074/jbc.M117.787572

Experimental method

X-RAY DIFFRACTION (2.114 Å)