5V7P
Atomic structure of the eukaryotic intramembrane Ras methyltransferase ICMT (isoprenylcysteine carboxyl methyltransferase), in complex with a monobody
Summary for 5V7P
| Entry DOI | 10.2210/pdb5v7p/pdb |
| Descriptor | Protein-S-isoprenylcysteine O-methyltransferase, monobody, S-ADENOSYL-L-HOMOCYSTEINE, ... (7 entities in total) |
| Functional Keywords | membrane protein, membrane enzyme, methyltransferase, lcp, transferase |
| Biological source | Tribolium castaneum (Red flour beetle) More |
| Cellular location | Endoplasmic reticulum membrane ; Multi-pass membrane protein : D6WJ77 |
| Total number of polymer chains | 2 |
| Total formula weight | 48976.35 |
| Authors | Long, S.B.,Diver, M.M.,Pedi, L.,Koide, A.,Koide, S. (deposition date: 2017-03-20, release date: 2018-01-17, Last modification date: 2024-03-06) |
| Primary citation | Diver, M.M.,Pedi, L.,Koide, A.,Koide, S.,Long, S.B. Atomic structure of the eukaryotic intramembrane RAS methyltransferase ICMT. Nature, 553:526-529, 2018 Cited by PubMed: 29342140DOI: 10.1038/nature25439 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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