5V7P
Atomic structure of the eukaryotic intramembrane Ras methyltransferase ICMT (isoprenylcysteine carboxyl methyltransferase), in complex with a monobody
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein-S-isoprenylcysteine O-methyltransferase | polymer | 288 | 32857.2 | 1 | UniProt (D6WJ77) Pfam (PF04140) | Tribolium castaneum (Red flour beetle) | |
| 2 | B (D) | monobody | polymer | 95 | 10135.4 | 1 | synthetic construct | ||
| 3 | C (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) | |||
| 4 | D, E, K (A) | UNDECANE | non-polymer | 156.3 | 3 | Chemie (UND) | |||
| 5 | F, G, H, I, J... (A) | DECANE | non-polymer | 142.3 | 11 | Chemie (D10) | |||
| 6 | AA, R, S, T, U... (A) | [(Z)-octadec-9-enyl] (2R)-2,3-bis(oxidanyl)propanoate | non-polymer | 356.5 | 10 | Chemie (MPG) | |||
| 7 | BA, CA (A, D) | water | water | 18.0 | 92 | Chemie (HOH) |
Sequence modifications
A: 1 - 281 (UniProt: D6WJ77)
| PDB | External Database | Details |
|---|---|---|
| Ala 282 | - | expression tag |
| Ala 283 | - | expression tag |
| Glu 284 | - | expression tag |
| Gly 285 | - | expression tag |
| Glu 286 | - | expression tag |
| Glu 287 | - | expression tag |
| Phe 288 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42992.5 | |
| Non-Polymers* | Number of molecules | 25 |
| Total formula weight | 5983.8 | |
| All* | Total formula weight | 48976.4 |
