Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004671 | molecular_function | protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0005789 | cellular_component | endoplasmic reticulum membrane |
| A | 0006481 | biological_process | C-terminal protein methylation |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0016020 | cellular_component | membrane |
| A | 0016740 | molecular_function | transferase activity |
| A | 0032259 | biological_process | methylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | binding site for residue SAH A 301 |
| Chain | Residue |
| A | ASN183 |
| A | HIS209 |
| A | PRO210 |
| A | SER211 |
| A | TYR212 |
| A | GLU250 |
| A | LEU254 |
| A | HOH413 |
| A | HOH415 |
| A | HOH427 |
| A | PHE184 |
| A | ASN185 |
| A | GLN189 |
| A | HIS196 |
| A | VAL197 |
| A | LEU198 |
| A | VAL199 |
| A | TYR204 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | binding site for residue UND A 302 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue UND A 303 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue D10 A 304 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue D10 A 305 |
| Chain | Residue |
| A | TYR217 |
| A | THR271 |
| A | GLY272 |
| A | ILE273 |
| A | ILE276 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | binding site for residue D10 A 306 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue D10 A 308 |
| Chain | Residue |
| A | LEU71 |
| A | MET99 |
| A | TRP139 |
| A | D10310 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue UND A 309 |
| Chain | Residue |
| A | SER137 |
| A | ILE144 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue D10 A 310 |
| Chain | Residue |
| A | ILE81 |
| A | D10308 |
| A | D10311 |
| A | MPG323 |
| site_id | AD1 |
| Number of Residues | 1 |
| Details | binding site for residue D10 A 311 |
| site_id | AD2 |
| Number of Residues | 1 |
| Details | binding site for residue D10 A 312 |
| site_id | AD3 |
| Number of Residues | 2 |
| Details | binding site for residue D10 A 313 |
| Chain | Residue |
| A | PHE148 |
| A | PHE149 |
| site_id | AD4 |
| Number of Residues | 2 |
| Details | binding site for residue D10 A 314 |
| Chain | Residue |
| A | PHE70 |
| A | TYR131 |
| site_id | AD5 |
| Number of Residues | 1 |
| Details | binding site for residue D10 A 315 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue MPG A 316 |
| Chain | Residue |
| A | SER128 |
| A | VAL171 |
| D | TYR78 |
| D | TYR79 |
| D | HOH114 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue MPG A 317 |
| Chain | Residue |
| A | LYS82 |
| A | LEU83 |
| A | GLN90 |
| A | HIS156 |
| A | ASN160 |
| site_id | AD8 |
| Number of Residues | 9 |
| Details | binding site for residue MPG A 318 |
| Chain | Residue |
| A | PRO4 |
| A | LYS7 |
| A | ILE8 |
| A | GLN11 |
| A | PHE56 |
| A | TYR57 |
| D | ALA12 |
| D | LEU19 |
| D | HOH124 |
| site_id | AD9 |
| Number of Residues | 5 |
| Details | binding site for residue MPG A 319 |
| Chain | Residue |
| A | MPG321 |
| D | VAL1 |
| D | ALA26 |
| D | VAL27 |
| D | TYR78 |
| site_id | AE1 |
| Number of Residues | 7 |
| Details | binding site for residue MPG A 320 |
| Chain | Residue |
| A | GLY31 |
| A | ILE32 |
| A | THR33 |
| A | VAL37 |
| A | PHE216 |
| A | ILE220 |
| A | TRP240 |
| site_id | AE2 |
| Number of Residues | 8 |
| Details | binding site for residue MPG A 321 |
| Chain | Residue |
| A | LEU178 |
| A | THR179 |
| A | HIS201 |
| A | MPG319 |
| A | MPG322 |
| D | VAL1 |
| D | SER2 |
| D | SER3 |
| site_id | AE3 |
| Number of Residues | 5 |
| Details | binding site for residue MPG A 322 |
| Chain | Residue |
| A | TYR30 |
| A | LEU237 |
| A | MET241 |
| A | MPG321 |
| D | PRO81 |
| site_id | AE4 |
| Number of Residues | 5 |
| Details | binding site for residue MPG A 323 |
| Chain | Residue |
| A | THR33 |
| A | THR39 |
| A | TYR80 |
| A | VAL84 |
| A | D10310 |
| site_id | AE5 |
| Number of Residues | 7 |
| Details | binding site for residue MPG A 324 |
| Chain | Residue |
| A | ALA234 |
| A | LEU237 |
| A | ILE23 |
| A | PHE26 |
| A | ASN27 |
| A | TYR45 |
| A | PRO233 |
| site_id | AE6 |
| Number of Residues | 11 |
| Details | binding site for residue MPG A 325 |
| Chain | Residue |
| A | TYR95 |
| A | MET99 |
| A | ASN126 |
| A | TYR131 |
| A | TRP215 |
| A | SER219 |
| A | THR222 |
| A | GLN223 |
| A | TYR235 |
| A | SER239 |
| D | TRP80 |
Functional Information from PROSITE/UniProt
| site_id | PS00687 |
| Number of Residues | 8 |
| Details | ALDEHYDE_DEHYDR_GLU Aldehyde dehydrogenases glutamic acid active site. GETGGNSP |
| Chain | Residue | Details |
| D | GLY37-PRO44 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | MET1-LEU2 | |
| A | LYS54-ASN58 | |
| A | GLN114-VAL118 | |
| A | SER182-ARG208 | |
| A | LYS244-ILE281 | |
| Chain | Residue | Details |
| A | SER3-TYR29 | |
| A | VAL36-LEU53 | |
| A | GLU59-ALA85 | |
| A | ILE89-VAL113 | |
| A | SER119-PHE149 | |
| A | HIS156-GLY181 | |
| A | HIS209-LEU226 | |
| A | LEU230-PHE243 | |
| Chain | Residue | Details |
| A | TYR30-LEU35 | |
| A | PRO86-ASN88 | |
| A | PRO150-ILE155 | |
| A | ILE227-PRO229 | |
| Chain | Residue | Details |
| A | GLN189 | |
| A | HIS196 | |
| A | TYR204 | |
| A | HIS209 | |
| A | GLU250 | |
| Chain | Residue | Details |
| A | ARG246 | |
