5V1P

DNA polymerase beta substrate complex with 8-oxoG:C at the primer terminus and incoming dCTP analog

Summary for 5V1P

• Entry DOI: 10.2210/pdb5v1p/pdb
• Related: 5vif 5vig 5vih 5vii 5vij 5vin 5vio 5vir
• Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*GP*CP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(8OG))-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... (9 entities in total)
• Functional Keywords: transferase ligase / dna, transferase-dna, ligase-dna complex, transferase/dna, ligase/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 48425.45

Authors

Freudenthal, B.D.,Smith, M.R.,Whitaker, A.M.,Schaich, M.A. (deposition date: 2017-03-02, release date: 2017-05-10, Last modification date: 2024-03-06)

• Primary citation: Whitaker, A.M.,Smith, M.R.,Schaich, M.A.,Freudenthal, B.D.; Capturing a mammalian DNA polymerase extending from an oxidized nucleotide.; Nucleic Acids Res., 45:6934-6944, 2017; PubMed: 28449123; DOI: 10.1093/nar/gkx293

Experimental method

X-RAY DIFFRACTION (1.991 Å)