5UZ9

Cryo EM structure of anti-CRISPRs, AcrF1 and AcrF2, bound to type I-F crRNA-guided CRISPR surveillance complex

Summary for 5UZ9

Entry DOI	10.2210/pdb5uz9/pdb
EMDB information	8624
Descriptor	CRISPR-associated protein Csy1, CRISPR-associated protein Csy2, CRISPR-associated protein Csy3, ... (7 entities in total)
Functional Keywords	crispr rna-recognition-motif (rrm), pseudo-helical, type 1-f crispr, immune system-rna complex, immune system/rna
Biological source	Pseudomonas aeruginosa (strain UCBPP-PA14) More
Total number of polymer chains	13
Total formula weight	379215.91
Authors	Chowdhury, S.,Carter, J.,Rollins, M.F.,Jackson, R.N.,Hoffmann, C.,Nosaka, L.,Bondy-Denomy, J.,Maxwell, K.L.,Davidson, A.R.,Fischer, E.R.,Lander, G.C.,Wiedenheft, B. (deposition date: 2017-02-25, release date: 2017-04-26, Last modification date: 2024-03-13)
Primary citation	Chowdhury, S.,Carter, J.,Rollins, M.F.,Golden, S.M.,Jackson, R.N.,Hoffmann, C.,Nosaka, L.,Bondy-Denomy, J.,Maxwell, K.L.,Davidson, A.R.,Fischer, E.R.,Lander, G.C.,Wiedenheft, B. Structure Reveals Mechanisms of Viral Suppressors that Intercept a CRISPR RNA-Guided Surveillance Complex. Cell, 169:47-57.e11, 2017 Cited by PubMed: 28340349 DOI: 10.1016/j.cell.2017.03.012 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.4 Å)

Structure validation