5UUV

Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Bacillus anthracis in the complex with a product IMP and the inhibitor P182

5UUV の概要

• エントリーDOI: 10.2210/pdb5uuv/pdb
• 関連するPDBエントリー: 3TSB 3TSD 3USB 4MJM 4MY1 4MY8 4MY9 4MYA 4MYX 4QM1 5URR 5URS 5uuw 5uuz
• 分子名称: Inosine-5'-monophosphate dehydrogenase, INOSINIC ACID, N-{4-chloro-3-[4-(trifluoromethyl)-1,3-thiazol-2-yl]phenyl}-N'-(2-{3-[(1E)-N-hydroxyethanimidoyl]phenyl}propan-2-yl)urea, ... (6 entities in total)
• 機能のキーワード: impdh, tim barrel, delta cbs, structural genomics, center for structural genomics of infectious diseases, csgid, oxidoreductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• 由来する生物種: Bacillus anthracis; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 166559.43

構造登録者

Kim, Y.,Maltseva, N.,Mulligan, R.,Makowska-Grzyska, M.,Gu, M.,Gollapalli, D.,Hedstrom, L.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2017-02-17, 公開日: 2017-03-01, 最終更新日: 2023-10-04)

• 主引用文献: Kim, Y.,Maltseva, N.,Mulligan, R.,Makowska-Grzyska, M.,Gu, M.,Gollapalli, D.,Hedstrom, L.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID); Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Bacillus anthracis in the complex with a product IMP and the inhibitor P182; To Be Published,

実験手法

X-RAY DIFFRACTION (2.75 Å)