Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003938 | molecular_function | IMP dehydrogenase activity |
| A | 0006164 | biological_process | purine nucleotide biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0003938 | molecular_function | IMP dehydrogenase activity |
| B | 0006164 | biological_process | purine nucleotide biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0003938 | molecular_function | IMP dehydrogenase activity |
| C | 0006164 | biological_process | purine nucleotide biosynthetic process |
| C | 0016491 | molecular_function | oxidoreductase activity |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0003938 | molecular_function | IMP dehydrogenase activity |
| D | 0006164 | biological_process | purine nucleotide biosynthetic process |
| D | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue IMP A 501 |
| Chain | Residue |
| A | ALA49 |
| A | GLY343 |
| A | LEU363 |
| A | GLY364 |
| A | SER365 |
| A | TYR388 |
| A | GLY390 |
| A | MET391 |
| A | GLY392 |
| A | GLU416 |
| A | 8L1502 |
| A | MET51 |
| A | ASN280 |
| A | GLY305 |
| A | SER306 |
| A | ILE307 |
| A | CYS308 |
| A | ASP341 |
| A | GLY342 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | binding site for residue 8L1 A 502 |
| Chain | Residue |
| A | THR252 |
| A | ALA253 |
| A | SER257 |
| A | VAL260 |
| A | THR310 |
| A | MET391 |
| A | VAL414 |
| A | GLU416 |
| A | IMP501 |
| D | LEU26 |
| D | ALA441 |
| D | GLY444 |
| D | TYR445 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue K A 503 |
| Chain | Residue |
| A | GLY303 |
| A | GLY305 |
| A | CYS308 |
| D | GLU470 |
| D | SER471 |
| D | HIS472 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue K A 504 |
| Chain | Residue |
| A | GLU470 |
| A | SER471 |
| A | HIS472 |
| C | GLY303 |
| C | GLY305 |
| C | CYS308 |
| site_id | AC5 |
| Number of Residues | 19 |
| Details | binding site for residue IMP B 501 |
| Chain | Residue |
| B | ALA49 |
| B | MET51 |
| B | ASN280 |
| B | GLY305 |
| B | SER306 |
| B | ILE307 |
| B | CYS308 |
| B | ASP341 |
| B | GLY342 |
| B | GLY343 |
| B | GLY364 |
| B | SER365 |
| B | TYR388 |
| B | GLY390 |
| B | MET391 |
| B | GLY392 |
| B | GLU416 |
| B | GLY417 |
| B | 8L1502 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | binding site for residue 8L1 B 502 |
| Chain | Residue |
| B | THR252 |
| B | SER257 |
| B | THR310 |
| B | MET391 |
| B | VAL414 |
| B | GLU416 |
| B | IMP501 |
| C | PRO27 |
| C | GLY444 |
| C | TYR445 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue K B 503 |
| Chain | Residue |
| B | GLY303 |
| B | GLY305 |
| B | CYS308 |
| C | GLU470 |
| C | SER471 |
| C | HIS472 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 504 |
| Chain | Residue |
| B | PRO272 |
| B | SER273 |
| B | ASN275 |
| B | ASN296 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue K B 505 |
| Chain | Residue |
| B | GLU470 |
| B | SER471 |
| B | HIS472 |
| D | GLY303 |
| D | GLY305 |
| D | CYS308 |
| site_id | AD1 |
| Number of Residues | 20 |
| Details | binding site for residue IMP C 501 |
| Chain | Residue |
| C | MET362 |
| C | LEU363 |
| C | GLY364 |
| C | SER365 |
| C | TYR388 |
| C | GLY390 |
| C | MET391 |
| C | GLY392 |
| C | GLU416 |
| C | 8L1502 |
| C | ALA49 |
| C | MET51 |
| C | ASN280 |
| C | GLY305 |
| C | SER306 |
| C | ILE307 |
| C | CYS308 |
| C | ASP341 |
| C | GLY342 |
| C | GLY343 |
| site_id | AD2 |
| Number of Residues | 9 |
| Details | binding site for residue 8L1 C 502 |
| Chain | Residue |
| A | ALA441 |
| A | GLY444 |
| C | THR252 |
| C | ALA253 |
| C | SER257 |
| C | THR310 |
| C | MET391 |
| C | GLU416 |
| C | IMP501 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue GOL C 503 |
| Chain | Residue |
| C | SER39 |
| C | ARG268 |
| C | SER273 |
| C | LEU274 |
| C | ASN275 |
| C | ASN296 |
| site_id | AD4 |
| Number of Residues | 19 |
| Details | binding site for residue IMP D 500 |
| Chain | Residue |
| D | ALA49 |
| D | MET51 |
| D | GLY305 |
| D | SER306 |
| D | ILE307 |
| D | CYS308 |
| D | THR310 |
| D | ASP341 |
| D | GLY342 |
| D | GLY343 |
| D | GLY364 |
| D | SER365 |
| D | TYR388 |
| D | GLY390 |
| D | MET391 |
| D | GLY392 |
| D | GLU416 |
| D | GLY417 |
| D | 8L1501 |
| site_id | AD5 |
| Number of Residues | 12 |
| Details | binding site for residue 8L1 D 501 |
| Chain | Residue |
| B | LEU26 |
| B | GLY444 |
| B | TYR445 |
| D | VAL229 |
| D | THR252 |
| D | ALA253 |
| D | SER257 |
| D | THR310 |
| D | MET391 |
| D | VAL414 |
| D | GLU416 |
| D | IMP500 |
Functional Information from PROSITE/UniProt
| site_id | PS00487 |
| Number of Residues | 13 |
| Details | IMP_DH_GMP_RED IMP dehydrogenase / GMP reductase signature. VKVGIGpGSICtT |
| Chain | Residue | Details |
| A | VAL298-THR310 | |
