5UMM

CRYSTAL STRUCTURE OF HUMAN MDM2 IN COMPLEX WITH 12-MER PEPTIDE INHIBITOR M3

Summary for 5UMM

• Entry DOI: 10.2210/pdb5umm/pdb
• Related: 5UML
• Descriptor: E3 ubiquitin-protein ligase Mdm2, PEPTIDE INHIBITOR M3, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: p53 binding protein, oncoprotein, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 23210.82

Authors

Pazgier, M.,Gohain, N.,Tolbert, W.D. (deposition date: 2017-01-27, release date: 2018-01-31, Last modification date: 2023-10-04)

• Primary citation: Pazgier, M.,Gohain, N.,Tolbert, W.D.; Design of ultrahigh-affinity and dual-specificity peptide antagonists of MDM2 and MDMX for p53 activation; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.65 Å)