5UMM

CRYSTAL STRUCTURE OF HUMAN MDM2 IN COMPLEX WITH 12-MER PEPTIDE INHIBITOR M3

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005634	cellular_component	nucleus
A	0043066	biological_process	negative regulation of apoptotic process
A	0051726	biological_process	regulation of cell cycle
C	0005634	cellular_component	nucleus
C	0043066	biological_process	negative regulation of apoptotic process
C	0051726	biological_process	regulation of cell cycle

Functional Information from PDB Data

site_id	AC1
Number of Residues	15
Details	binding site for Di-peptide CL D 101 and GLN C 44

Chain	Residue
C	LYS39
C	ILE103
C	TYR104
C	ARG105
D	LEU1
D	GLU5
D	GLU5
C	GLY42
C	ALA43
C	LYS45
C	ARG97
C	LYS98
C	ILE99
C	TYR100
C	MET102

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