5U1I

Crystal structure of a methyltransferase involved in the biosynthesis of gentamicin in complex with the methylated Kanamycin B

Summary for 5U1I

• Entry DOI: 10.2210/pdb5u1i/pdb
• Related: 5U0N 5U0T 5U18 5U19 5U1E
• Descriptor: Putative gentamicin methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: gentamicin methyltransferase sah methylated kanamycin b, transferase
• Biological source: Micromonospora echinospora
• Total number of polymer chains: 1
• Total formula weight: 38373.93

Authors

Bury, P.,Huang, F.,Leadlay, P.,Dias, M.V.B. (deposition date: 2016-11-28, release date: 2017-11-01, Last modification date: 2023-10-04)

• Primary citation: Bury, P.D.S.,Huang, F.,Li, S.,Sun, Y.,Leadlay, P.F.,Dias, M.V.B.; Structural Basis of the Selectivity of GenN, an Aminoglycoside N-Methyltransferase Involved in Gentamicin Biosynthesis.; ACS Chem. Biol., 12:2779-2787, 2017; PubMed: 28876898; DOI: 10.1021/acschembio.7b00466

Experimental method

X-RAY DIFFRACTION (1.932 Å)