5U1I

Crystal structure of a methyltransferase involved in the biosynthesis of gentamicin in complex with the methylated Kanamycin B

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0008168	molecular_function	methyltransferase activity
A	0008757	molecular_function	S-adenosylmethionine-dependent methyltransferase activity
A	0032259	biological_process	methylation
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	23
Details	binding site for residue SAH A 401

Chain	Residue
A	ASP107
A	MET180
A	ASN194
A	PRO196
A	LEU207
A	LEU208
A	ILE214
A	7QM403
A	HOH510
A	HOH516
A	HOH526
A	GLY131
A	HOH558
A	HOH570
A	HOH582
A	HOH588
A	CYS132
A	GLY133
A	VAL136
A	LEU137
A	ASP152
A	VAL153
A	ASP179

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site_id	AC2
Number of Residues	6
Details	binding site for residue CA A 402

Chain	Residue
A	GLU98
A	ASP206
A	HOH556
A	HOH569
A	HOH626
A	HOH632

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site_id	AC3
Number of Residues	18
Details	binding site for residue 7QM A 403

Chain	Residue
A	ASP95
A	VAL96
A	GLU98
A	GLN101
A	ASP107
A	TRP110
A	GLU111
A	ASN194
A	SER195
A	PRO196
A	ASN198
A	LEU208
A	GLU209
A	ASN235
A	ARG281
A	SAH401
A	HOH538
A	HOH595

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