5U0P

Cryo-EM structure of the transcriptional Mediator

Summary for 5U0P

• Entry DOI: 10.2210/pdb5u0p/pdb
• Related: 5U0S
• EMDB information: 8479 8480
• Descriptor: Mediator complex subunit 14, Mediator complex subunit 7, Mediator complex subunit 21, ... (16 entities in total)
• Functional Keywords: transcription, transcriptional, mediator, head, middle, tail, srb, rna polymerase ii, med
• Biological source: Schizosaccharomyces pombe (Fission yeast); More
• Total number of polymer chains: 16
• Total formula weight: 455878.23

Authors

Tsai, K.-L.,Yu, X.,Gopalan, S.,Chao, T.-C.,Zhang, Y.,Florens, L.,Washburn, M.P.,Murakami, K.,Conaway, R.C.,Conaway, J.W.,Asturias, F. (deposition date: 2016-11-26, release date: 2017-03-08, Last modification date: 2024-03-13)

• Primary citation: Tsai, K.L.,Yu, X.,Gopalan, S.,Chao, T.C.,Zhang, Y.,Florens, L.,Washburn, M.P.,Murakami, K.,Conaway, R.C.,Conaway, J.W.,Asturias, F.J.; Mediator structure and rearrangements required for holoenzyme formation.; Nature, 544:196-201, 2017; PubMed: 28241144; DOI: 10.1038/nature21393

Experimental method

ELECTRON MICROSCOPY (4.4 Å)