5TZT
Crystal structure of human CD47 ECD bound to Fab of C47B161
Summary for 5TZT
Entry DOI | 10.2210/pdb5tzt/pdb |
Related | 5TZ2 5TZU |
Descriptor | Light Chain of Fab C47B161, Heavy Chain of Fab C47B161, Leukocyte surface antigen CD47, ... (6 entities in total) |
Functional Keywords | antigen-fab complex, immunoglobulin, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 6 |
Total formula weight | 127523.48 |
Authors | Cardoso, R.M.F. (deposition date: 2016-11-22, release date: 2017-03-15, Last modification date: 2023-10-04) |
Primary citation | Pietsch, E.C.,Dong, J.,Cardoso, R.,Zhang, X.,Chin, D.,Hawkins, R.,Dinh, T.,Zhou, M.,Strake, B.,Feng, P.H.,Rocca, M.,Santos, C.D.,Shan, X.,Danet-Desnoyers, G.,Shi, F.,Kaiser, E.,Millar, H.J.,Fenton, S.,Swanson, R.,Nemeth, J.A.,Attar, R.M. Anti-leukemic activity and tolerability of anti-human CD47 monoclonal antibodies. Blood Cancer J, 7:e536-e536, 2017 Cited by PubMed: 28234345DOI: 10.1038/bcj.2017.7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.89 Å) |
Structure validation
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