5TXT
Structure of asymmetric apo/holo ALAS dimer from S. cerevisiae
Summary for 5TXT
Entry DOI | 10.2210/pdb5txt/pdb |
Related | 5TXR |
Descriptor | 5-aminolevulinate synthase, mitochondrial, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, SULFATE ION, ... (5 entities in total) |
Functional Keywords | transferase, heme biosynthesis, 5-aminolevulinic acid, pyridoxal 5-phosphate |
Biological source | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) More |
Total number of polymer chains | 6 |
Total formula weight | 329044.35 |
Authors | Brown, B.L.,Grant, R.A.,Kardon, J.R.,Sauer, R.T.,Baker, T.A. (deposition date: 2016-11-17, release date: 2018-03-28, Last modification date: 2024-04-03) |
Primary citation | Brown, B.L.,Kardon, J.R.,Sauer, R.T.,Baker, T.A. Structure of the Mitochondrial Aminolevulinic Acid Synthase, a Key Heme Biosynthetic Enzyme. Structure, 26:580-589.e4, 2018 Cited by PubMed: 29551290DOI: 10.1016/j.str.2018.02.012 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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