5TWK

Crystal Structure of RlmH in Complex with Sinefungin

Summary for 5TWK

Entry DOI	10.2210/pdb5twk/pdb
Related	5TWJ
Descriptor	Ribosomal RNA large subunit methyltransferase H, SINEFUNGIN (3 entities in total)
Functional Keywords	sinefungin, rna methyltransferase, spout, pseudouridine, helix 69, transferase, transferase-antibiotic complex, transferase/antibiotic
Biological source	Escherichia coli
Total number of polymer chains	4
Total formula weight	74697.99
Authors	Koh, C.S.,Madireddy, R.,Beane, T.J.,Zamore, P.D.,Korostelev, A.A. (deposition date: 2016-11-14, release date: 2017-05-03, Last modification date: 2023-10-04)
Primary citation	Koh, C.S.,Madireddy, R.,Beane, T.J.,Zamore, P.D.,Korostelev, A.A. Small methyltransferase RlmH assembles a composite active site to methylate a ribosomal pseudouridine. Sci Rep, 7:969-969, 2017 Cited by PubMed: 28428565 DOI: 10.1038/s41598-017-01186-5 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation