5TWK

Crystal Structure of RlmH in Complex with Sinefungin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	C, D, A, B	Ribosomal RNA large subunit methyltransferase H	polymer	162	18293.1	4	UniProt (B7MFQ9) Pfam (PF02590) UniProt (by SIFTS) (P0A8I8) In PDB	Escherichia coli	23S rRNA (pseudouridine1915-N3)-methyltransferase,23S rRNA m3Psi1915 methyltransferase,rRNA (pseudouridine-N3-)-methyltransferase RlmH
2	C, D, A, B	SINEFUNGIN	non-polymer		381.4	4	Chemie (SFG)
3		water	water		18.0	210	Chemie (HOH)

Sequence modifications

C, D, A, B: 2 - 155 (UniProt: B7MFQ9)

PDB	External Database	Details
Met -6	-	initiating methionine
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Val 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	73172.4
Non-Polymers*	Number of molecules	4
	Total formula weight	1525.5
All*	Total formula weight	74698.0

*Water molecules are not included.