5T5C
A Novel domain in human EXOG converts apoptotic endonuclease to DNA-repair enzyme
Summary for 5T5C
Entry DOI | 10.2210/pdb5t5c/pdb |
Related | 5T3V 5T40 5T4I |
Descriptor | Nuclease EXOG, mitochondrial, DNA (5'-D(P*CP*TP*GP*AP*CP*GP*TP*GP*C)-3'), DNA (5'-D(P*GP*CP*AP*CP*GP*TP*CP*AP*G)-3'), ... (5 entities in total) |
Functional Keywords | mitochondria, exonuclease, dna-repair, complex, hydrolase-dna complex, hydrolase/dna |
Biological source | Homo sapiens (Human) More |
Cellular location | Mitochondrion inner membrane : Q9Y2C4 |
Total number of polymer chains | 6 |
Total formula weight | 83544.13 |
Authors | Szymanski, M.R.,Yin, W.Y. (deposition date: 2016-08-30, release date: 2017-05-17, Last modification date: 2023-10-04) |
Primary citation | Szymanski, M.R.,Yu, W.,Gmyrek, A.M.,White, M.A.,Molineux, I.J.,Lee, J.C.,Yin, Y.W. A domain in human EXOG converts apoptotic endonuclease to DNA-repair exonuclease. Nat Commun, 8:14959-14959, 2017 Cited by PubMed: 28466855DOI: 10.1038/ncomms14959 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.851 Å) |
Structure validation
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