5T4I

A Novel domain in human EXOG converts apoptotic endonuclease to DNA-repair enzyme

Summary for 5T4I

• Entry DOI: 10.2210/pdb5t4i/pdb
• Related: 5T3V 5T40 5T5C
• Descriptor: Nuclease EXOG, mitochondrial, DNA (5'-D(P*CP*TP*GP*AP*CP*GP*TP*GP*C)-3'), DNA (5'-D(*GP*CP*AP*CP*GP*TP*CP*AP*G)-3'), ... (5 entities in total)
• Functional Keywords: mitochondria, exonuclease, dna-repair, complex, hydrolase-dna complex, hydrolase/dna
• Biological source: Homo sapiens (Human); More
• Cellular location: Mitochondrion inner membrane : Q9Y2C4
• Total number of polymer chains: 6
• Total formula weight: 83605.40

Authors

Szymanski, M.R.,Yin, W.Y. (deposition date: 2016-08-29, release date: 2017-05-17, Last modification date: 2023-10-04)

• Primary citation: Szymanski, M.R.,Yu, W.,Gmyrek, A.M.,White, M.A.,Molineux, I.J.,Lee, J.C.,Yin, Y.W.; A domain in human EXOG converts apoptotic endonuclease to DNA-repair exonuclease.; Nat Commun, 8:14959-14959, 2017; PubMed: 28466855; DOI: 10.1038/ncomms14959

Experimental method

X-RAY DIFFRACTION (2.389 Å)