5T4I
A Novel domain in human EXOG converts apoptotic endonuclease to DNA-repair enzyme
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Nuclease EXOG, mitochondrial | polymer | 317 | 36275.2 | 2 | UniProt (Q9Y2C4) Pfam (PF01223) Pfam (PF18026) In PDB | Homo sapiens (Human) | Endonuclease G-like 1,Endo G-like 1 |
2 | C, E | DNA (5'-D(P*CP*TP*GP*AP*CP*GP*TP*GP*C)-3') | polymer | 9 | 2731.8 | 2 | DNA launch vector pDE-GFP2 | ||
3 | D, F | DNA (5'-D(*GP*CP*AP*CP*GP*TP*CP*AP*G)-3') | polymer | 9 | 2740.8 | 2 | DNA launch vector pDE-GFP2 | ||
4 | A, B | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
5 | water | water | 18.0 | 53 | Chemie (HOH) |
Sequence modifications
A, B: 59 - 368 (UniProt: Q9Y2C4)
PDB | External Database | Details |
---|---|---|
Met 58 | - | initiating methionine |
Ala 140 | His 140 | engineered mutation |
His 369 | - | expression tag |
His 370 | - | expression tag |
His 371 | - | expression tag |
His 372 | - | expression tag |
His 373 | - | expression tag |
His 374 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 83495.5 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 109.9 | |
All* | Total formula weight | 83605.4 |