5T46
Crystal structure of the human eIF4E-eIF4G complex
Summary for 5T46
Entry DOI | 10.2210/pdb5t46/pdb |
Descriptor | Eukaryotic translation initiation factor 4E, Eukaryotic translation initiation factor 4 gamma 1, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, ... (5 entities in total) |
Functional Keywords | translation, gene regulation, cap binding protein, 4e-binding protein, translation initiation, eif4f |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm, P-body : P06730 |
Total number of polymer chains | 4 |
Total formula weight | 68480.61 |
Authors | Gruener, S.,Peter, D.,Weber, R.,Wohlbold, L.,Chung, M.-Y.,Weichenrieder, O.,Valkov, E.,Igreja, C.,Izaurralde, E. (deposition date: 2016-08-29, release date: 2016-10-26, Last modification date: 2024-01-17) |
Primary citation | Gruner, S.,Peter, D.,Weber, R.,Wohlbold, L.,Chung, M.Y.,Weichenrieder, O.,Valkov, E.,Igreja, C.,Izaurralde, E. The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation. Mol.Cell, 64:467-479, 2016 Cited by PubMed: 27773676DOI: 10.1016/j.molcel.2016.09.020 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.53 Å) |
Structure validation
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