5T46

Crystal structure of the human eIF4E-eIF4G complex

5T46 の概要

• エントリーDOI: 10.2210/pdb5t46/pdb
• 分子名称: Eukaryotic translation initiation factor 4E, Eukaryotic translation initiation factor 4 gamma 1, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, ... (5 entities in total)
• 機能のキーワード: translation, gene regulation, cap binding protein, 4e-binding protein, translation initiation, eif4f
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Cytoplasm, P-body : P06730
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 68480.61

構造登録者

Gruener, S.,Peter, D.,Weber, R.,Wohlbold, L.,Chung, M.-Y.,Weichenrieder, O.,Valkov, E.,Igreja, C.,Izaurralde, E. (登録日: 2016-08-29, 公開日: 2016-10-26, 最終更新日: 2024-01-17)

• 主引用文献: Gruner, S.,Peter, D.,Weber, R.,Wohlbold, L.,Chung, M.Y.,Weichenrieder, O.,Valkov, E.,Igreja, C.,Izaurralde, E.; The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation.; Mol.Cell, 64:467-479, 2016; PubMed: 27773676; DOI: 10.1016/j.molcel.2016.09.020

実験手法

X-RAY DIFFRACTION (1.53 Å)