5SVT
Anomalous Cs+ signal reveals the site of Na+ ion entry to the channel pore of the human P2X3 ion channel through the extracellular fenestrations
Summary for 5SVT
Entry DOI | 10.2210/pdb5svt/pdb |
Related | 5SVJ 5SVK 5SVL 5SVM 5SVP 5SVQ 5SVR 5SVS |
Descriptor | P2X purinoceptor 3, 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | membrane protein, ion channel, anomalous signal |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 41456.84 |
Authors | Mansoor, S.E.,Lu, W.,Oosterheert, W.,Shekhar, M.,Tajkhorshid, E.,Gouaux, E. (deposition date: 2016-08-07, release date: 2016-09-28, Last modification date: 2020-07-29) |
Primary citation | Mansoor, S.E.,Lu, W.,Oosterheert, W.,Shekhar, M.,Tajkhorshid, E.,Gouaux, E. X-ray structures define human P2X3 receptor gating cycle and antagonist action. Nature, 538:66-71, 2016 Cited by PubMed: 27626375DOI: 10.1038/nature19367 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.794 Å) |
Structure validation
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