5OVW

Nanobody-bound BtuF, the vitamin B12 binding protein in Escherichia coli

Summary for 5OVW

• Entry DOI: 10.2210/pdb5ovw/pdb
• Descriptor: Vitamin B12-binding protein, Nanobody, GLYCEROL, ... (4 entities in total)
• Functional Keywords: nanobody, inhibitor, vitamin b12, substrate-binding protein, transport protein
• Biological source: Escherichia coli; More
• Total number of polymer chains: 12
• Total formula weight: 291321.92

Authors

Mireku, S.A.,Sauer, M.M.,Glockshuber, R.,Locher, K.P. (deposition date: 2017-08-30, release date: 2017-11-08, Last modification date: 2019-10-16)

• Primary citation: Mireku, S.A.,Sauer, M.M.,Glockshuber, R.,Locher, K.P.; Structural basis of nanobody-mediated blocking of BtuF, the cognate substrate-binding protein of the Escherichia coli vitamin B12 transporter BtuCD.; Sci Rep, 7:14296-14296, 2017; PubMed: 29084999; DOI: 10.1038/s41598-017-14512-8

Experimental method

X-RAY DIFFRACTION (2.653 Å)