5OTT

Extracellular domain of GLP-1 receptor in complex with exendin-4 variant Gly2Hcs/Thr5Hcs

Summary for 5OTT

• Entry DOI: 10.2210/pdb5ott/pdb
• Descriptor: Glucagon-like peptide 1 receptor, Exendin-4 (3 entities in total)
• Functional Keywords: glucagon-like peptide 1, gpcr, cyclic peptides, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 17815.66

Authors

Mortensen, S. (deposition date: 2017-08-22, release date: 2018-07-04, Last modification date: 2024-03-06)

• Primary citation: Oddo, A.,Mortensen, S.,Thogersen, H.,De Maria, L.,Hennen, S.,McGuire, J.N.,Kofoed, J.,Linderoth, L.,Reedtz-Runge, S.; alpha-Helix or beta-Turn? An Investigation into N-Terminally Constrained Analogues of Glucagon-like Peptide 1 (GLP-1) and Exendin-4.; Biochemistry, 57:4148-4154, 2018; PubMed: 29877701; DOI: 10.1021/acs.biochem.8b00105

Experimental method

X-RAY DIFFRACTION (1.92 Å)