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5OTT

Extracellular domain of GLP-1 receptor in complex with exendin-4 variant Gly2Hcs/Thr5Hcs

Functional Information from GO Data
ChainGOidnamespacecontents
A0004930molecular_functionG protein-coupled receptor activity
A0004967molecular_functionglucagon receptor activity
A0007186biological_processG protein-coupled receptor signaling pathway
A0008528molecular_functionG protein-coupled peptide receptor activity
A0016020cellular_componentmembrane
B0005179molecular_functionhormone activity
B0005576cellular_componentextracellular region
Functional Information from PROSITE/UniProt
site_idPS00649
Number of Residues25
DetailsG_PROTEIN_RECEP_F2_1 G-protein coupled receptors family 2 signature 1. CnrtFDeya.CWpdGepgsfvnvsCP
ChainResidueDetails
ACYS62-PRO86

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsSite: {"description":"Interaction with the endogenous ligand GLP-1","evidences":[{"source":"PubMed","id":"19861722","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues3
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"22412906","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

239149

PDB entries from 2025-07-23

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