5OTT

Extracellular domain of GLP-1 receptor in complex with exendin-4 variant Gly2Hcs/Thr5Hcs

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004930	molecular_function	G protein-coupled receptor activity
A	0004967	molecular_function	glucagon receptor activity
A	0007186	biological_process	G protein-coupled receptor signaling pathway
A	0008528	molecular_function	G protein-coupled peptide receptor activity
A	0016020	cellular_component	membrane
B	0005179	molecular_function	hormone activity
B	0005576	cellular_component	extracellular region

Functional Information from PROSITE/UniProt

site_id	PS00649
Number of Residues	25
Details	G_PROTEIN_RECEP_F2_1 G-protein coupled receptors family 2 signature 1. CnrtFDeya.CWpdGepgsfvnvsCP

Chain	Residue	Details
A	CYS62-PRO86

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: Serine amide => ECO:0000269|PubMed:1313797

Chain	Residue	Details
B	SER39

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site_id	SWS_FT_FI2
Number of Residues	2
Details	SITE: Interaction with the endogenous ligand GLP-1 => ECO:0000269|PubMed:19861722

Chain	Residue	Details
A	ARG121
A	GLU128

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site_id	SWS_FT_FI3
Number of Residues	3
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:22412906

Chain	Residue	Details
A	ASN63
A	ASN82
A	ASN115

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