5OTT
Extracellular domain of GLP-1 receptor in complex with exendin-4 variant Gly2Hcs/Thr5Hcs
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glucagon-like peptide 1 receptor | polymer | 116 | 13547.9 | 1 | UniProt (P43220) Pfam (PF02793) | Homo sapiens (Human) | GLP-1R |
| 2 | B (B) | Exendin-4 | polymer | 39 | 4267.8 | 1 | UniProt (P26349) Pfam (PF00123) | Heloderma suspectum | |
| 3 | C, D (A, B) | water | water | 18.0 | 118 | Chemie (HOH) |
Sequence modifications
B: 1 - 39 (UniProt: P26349)
| PDB | External Database | Details |
|---|---|---|
| Hcs 2 | Gly 49 | engineered mutation |
| Hcs 5 | Thr 52 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 17815.7 | |
| All* | Total formula weight | 17815.7 |
