5OL0
Structure of Leishmania infantum Silent Information Regulator 2 related protein 1 (LiSIR2rp1) in complex with acetylated p53 peptide
Summary for 5OL0
Entry DOI | 10.2210/pdb5ol0/pdb |
Descriptor | Putative silent information regulator 2,Putative silent information regulator 2, Cellular tumor antigen p53, ZINC ION, ... (4 entities in total) |
Functional Keywords | nad-dependent histone deacetylase, hydrolase |
Biological source | Leishmania infantum More |
Cellular location | Cytoplasm. Isoform 1: Nucleus. Isoform 2: Nucleus. Isoform 3: Nucleus. Isoform 4: Nucleus. Isoform 7: Nucleus. Isoform 8: Nucleus. Isoform 9: Cytoplasm: P04637 |
Total number of polymer chains | 4 |
Total formula weight | 75156.16 |
Authors | Ronin, C.,Ciesielski, F.,Ciapetti, P. (deposition date: 2017-07-26, release date: 2018-02-28, Last modification date: 2024-01-17) |
Primary citation | Ronin, C.,Costa, D.M.,Tavares, J.,Faria, J.,Ciesielski, F.,Ciapetti, P.,Smith, T.K.,MacDougall, J.,Cordeiro-da-Silva, A.,Pemberton, I.K. The crystal structure of the Leishmania infantum Silent Information Regulator 2 related protein 1: Implications to protein function and drug design. PLoS ONE, 13:e0193602-e0193602, 2018 Cited by PubMed: 29543820DOI: 10.1371/journal.pone.0193602 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.99 Å) |
Structure validation
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