5ODT

Aurora-A in complex with TACC3

Summary for 5ODT

• Entry DOI: 10.2210/pdb5odt/pdb
• Descriptor: Aurora kinase A, Transforming acidic coiled-coil-containing protein 3, ADENOSINE-5'-DIPHOSPHATE, ... (6 entities in total)
• Functional Keywords: mitotic kinase, transferase
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome : O14965; Cytoplasm : Q9Y6A5
• Total number of polymer chains: 2
• Total formula weight: 39125.17

Authors

Burgess, S.G.,Bayliss, R. (deposition date: 2017-07-06, release date: 2018-03-14, Last modification date: 2024-01-17)

• Primary citation: Burgess, S.G.,Mukherjee, M.,Sabir, S.,Joseph, N.,Gutierrez-Caballero, C.,Richards, M.W.,Huguenin-Dezot, N.,Chin, J.W.,Kennedy, E.J.,Pfuhl, M.,Royle, S.J.,Gergely, F.,Bayliss, R.; Mitotic spindle association of TACC3 requires Aurora-A-dependent stabilization of a cryptic alpha-helix.; EMBO J., 37:-, 2018; PubMed: 29510984; DOI: 10.15252/embj.201797902

Experimental method

X-RAY DIFFRACTION (2.021 Å)