5OCW
Structure of Mycobacterium tuberculosis tryptophan synthase in space group F222
Summary for 5OCW
Entry DOI | 10.2210/pdb5ocw/pdb |
Descriptor | Tryptophan synthase alpha chain, Tryptophan synthase beta chain, 2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]ACRYLIC ACID (3 entities in total) |
Functional Keywords | tryptophan synthesis mycobacterium tuberculosis, electron transport |
Biological source | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) More |
Total number of polymer chains | 24 |
Total formula weight | 925268.20 |
Authors | Futterer, K.,Abrahams, K.,Cox, J.A.G.,Besra, G.S. (deposition date: 2017-07-03, release date: 2017-07-12, Last modification date: 2024-01-17) |
Primary citation | Abrahams, K.A.,Cox, J.A.G.,Futterer, K.,Rullas, J.,Ortega-Muro, F.,Loman, N.J.,Moynihan, P.J.,Perez-Herran, E.,Jimenez, E.,Esquivias, J.,Barros, D.,Ballell, L.,Alemparte, C.,Besra, G.S. Inhibiting mycobacterial tryptophan synthase by targeting the inter-subunit interface. Sci Rep, 7:9430-9430, 2017 Cited by PubMed: 28842600DOI: 10.1038/s41598-017-09642-y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4 Å) |
Structure validation
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