5O76
Structure of phosphoY371 c-CBL in complex with ZAP70-peptide and UbV.pCBL ubiquitin variant
Summary for 5O76
Entry DOI | 10.2210/pdb5o76/pdb |
Descriptor | E3 ubiquitin-protein ligase CBL, Tyrosine protein kinase ZAP70 peptide, UbV.pCBL ubiquitin variant, ... (6 entities in total) |
Functional Keywords | e3 ring ligase, ubiquitin variant, ligase |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm: P22681 |
Total number of polymer chains | 6 |
Total formula weight | 111580.85 |
Authors | Gabrielsen, M.,Buetow, L.,Huang, D.T. (deposition date: 2017-06-08, release date: 2017-11-01, Last modification date: 2024-01-17) |
Primary citation | Gabrielsen, M.,Buetow, L.,Nakasone, M.A.,Ahmed, S.F.,Sibbet, G.J.,Smith, B.O.,Zhang, W.,Sidhu, S.S.,Huang, D.T. A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants. Mol. Cell, 68:456-470.e10, 2017 Cited by PubMed: 29053960DOI: 10.1016/j.molcel.2017.09.027 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.473 Å) |
Structure validation
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