5O76
Structure of phosphoY371 c-CBL in complex with ZAP70-peptide and UbV.pCBL ubiquitin variant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | E3 ubiquitin-protein ligase CBL | polymer | 391 | 45136.8 | 2 | UniProt (P22681) Pfam (PF02262) Pfam (PF02761) Pfam (PF02762) Pfam (PF00097) | Homo sapiens (Human) | Casitas B-lineage lymphoma proto-oncogene,Proto-oncogene c-Cbl,RING finger protein 55,RING-type E3 ubiquitin transferase CBL,Signal transduction protein CBL |
| 2 | B, D (B, D) | Tyrosine protein kinase ZAP70 peptide | polymer | 12 | 1344.3 | 2 | UniProt (by SIFTS) (P43403) | Homo sapiens | |
| 3 | E, F (E, F) | UbV.pCBL ubiquitin variant | polymer | 82 | 9138.4 | 2 | Homo sapiens | ||
| 4 | G, H, J, K (A, C) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 5 | I, L (A, C) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 6 | M, N, O, P, Q (A, B, C, E, F) | water | water | 18.0 | 235 | Chemie (HOH) |
Sequence modifications
A, C: 47 - 435 (UniProt: P22681)
| PDB | External Database | Details |
|---|---|---|
| Gly 45 | - | expression tag |
| Ser 46 | - | expression tag |
| Phe 368 | Tyr 368 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 111239.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 341.8 | |
| All* | Total formula weight | 111580.8 |
