5O1N
Crystal structure of human aminoadipate semialdehyde synthase, saccharopine dehydrogenase domain with N-[(2S)-2-Pyrrolidinylmethyl]-trifluoromethanesulfonamide bound
Summary for 5O1N
Entry DOI | 10.2210/pdb5o1n/pdb |
Descriptor | Alpha-aminoadipic semialdehyde synthase, mitochondrial, 1,1,1-tris(fluoranyl)-~{N}-[[(2~{S})-pyrrolidin-2-yl]methyl]methanesulfonamide, DIMETHYL SULFOXIDE, ... (6 entities in total) |
Functional Keywords | human aminoadipate semialdehyde synthase, saccharopine dehydrogenase domain with n-[(2s)-2-pyrrolidinylmethyl]-trifluoromethanesulfonamide bound, oxidoreductase |
Biological source | Homo sapiens (Human) |
Cellular location | Mitochondrion : Q9UDR5 |
Total number of polymer chains | 1 |
Total formula weight | 55087.36 |
Authors | Kopec, J.,Rembeza, E.,Pena, I.A.,Strain-Damerell, C.,Goubin, S.,Sethi, R.,Velupillai, S.,Talon, R.,Collins, P.,Krojer, T.,McLaughlin, M.,Burgess-Brown, N.,Arrowsmith, C.,Edwards, A.,Bountra, C.,Brennan, P.,von Delft, F.,Arruda, P.,Yue, W.W. (deposition date: 2017-05-18, release date: 2017-05-31, Last modification date: 2024-01-17) |
Primary citation | Kopec, J.,Yue, W.W. Crystal structure of human aminoadipate semialdehyde synthase, saccharopine dehydrogenase domain with N-[(2S)-2-Pyrrolidinylmethyl]-trifluoromethanesulfonamide bound To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.28 Å) |
Structure validation
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