5NZH

Crystal structure of UDP-glucose pyrophosphorylase V402W mutant from Leishmania major

Summary for 5NZH

• Entry DOI: 10.2210/pdb5nzh/pdb
• Related: 2OEF 2OEG 4J18 4M28 4M2A 4M2B
• Descriptor: UDP-glucose pyrophosphorylase (2 entities in total)
• Functional Keywords: ntp-transferase, pathogen, allostery, catalysis, transferase
• Biological source: Leishmania major
• Total number of polymer chains: 2
• Total formula weight: 112283.70

Authors

Cramer, J.T.,Fuehring, J.I.,Baruch, P.,Bruetting, C.,Hesse, R.,Knoelker, H.-J.,Gerardy-Schahn, R.,Fedorov, R. (deposition date: 2017-05-14, release date: 2018-04-18, Last modification date: 2024-10-16)

• Primary citation: Cramer, J.T.,Fuehring, J.I.,Baruch, P.,Bruetting, C.,Knoelker, H.-J.,Gerardy-Schahn, R.,Fedorov, R.; Decoding Allosteric Networks in Biocatalysts: Rational Approach to Therapies and Biotechnologies; Acs Catalysis, 8:-, 2018; DOI: 10.1021/acscatal.7b03714

Experimental method

X-RAY DIFFRACTION (2.9 Å)