5NZH

Crystal structure of UDP-glucose pyrophosphorylase V402W mutant from Leishmania major

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	UDP-glucose pyrophosphorylase	polymer	505	56141.9	2	UniProt (Q4QDU3) Pfam (PF01704) In PDB	Leishmania major
2		water	water		18.0	355	Chemie (HOH)

Sequence modifications

A, B: 1 - 494 (UniProt: Q4QDU3)

PDB	External Database	Details
Trp 402	Val 402	engineered mutation
Met 495	-	expression tag
Arg 496	-	expression tag
Pro 497	-	expression tag
Leu 498	-	expression tag
Glu 499	-	expression tag
His 500	-	expression tag
His 501	-	expression tag
His 502	-	expression tag
His 503	-	expression tag
His 504	-	expression tag
His 505	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	112283.7
All*	Total formula weight	112283.7

*Water molecules are not included.